Distinction (82) PCOL3012 notes

Description

Comprehensive and easy to understand notes for PCOL3012: Drug Design and Development. The notes are organised by lectures and lecture outcomes (if they were outcome) and diagrams and tables have been included to supplement the written text. Lectures include: L1: Course overview – chirality and thalidomide L2: Binding to a target – shape and intermolecular forces L3 and 4: Quantitative structure activity relationships 1 + 2 L5: Structure of drug targets: proteins L6: Receptors (and transporters) as drug targets L7: Cellular and Molecular Techniques (Protein crystallography) in neuropharmacology L8: Proteins as a drug target: antivirals L9 and 10: Quantitative Structure Activity – Opioids 1 & 2 L12: Polynucleotides as drug targets: cisplatin L14: Chelation therapy L15: Protein Therapeutics 1: New Therapeutic Opportunities L16: Protein Therapeutics 2: Production and Development L17: Drug Discovery: Finding a Lead L18: Drug Design: Optimising target interactions L19: Kinase inhibitors L20: Parameters used to describe drug activity L21: Prodrugs and drug transformations L22: Combinatorial synthesis L23: PET and SPECT agents 1 L24: PET and SPECT agents 2 L25: Big data in pharmacology L26: Isolation from Nature (the order of lectures may be different due to some lectures being quizzes etc)