HD (96) BMS2062 Introduction to Bioinformatics Notes

Description

Comprehensive notes covering weeks 1-12, summarising all key content from lectures in easy to understand language. Used by many students for HD marks. Lectures included: 1 – Review of Biopolymer Structure and Function, Amino Acid Group Ionisation & Peptide Concepts 2 – The Central Dogma of Molecular Biology & The Language of DNA 3 – RNA - Function Through Folding 4 – Genome Annotation 5 – Genome Sequencing 6 – The Human Genome Project 7 – Examining the Transcriptome 8 – Functional Genomics 9 – Exploiting Genomic Information 10 – From mRNA to Functional Protein 11 – One Gene, Many Proteins - Proteomics 12 – Inflammation, Malaria, and HIV - Chemokine Receptors and Sulfation 13 – Enzymes 14 – Protein Families 15 – Protein Structure and Interaction using NMR Spectroscopy 16 – Protein Binding and Recognition 17 – Crystal Structure Determination and the Protein Databank 18 – One Protein – Multiple Structures – Multiple Functions 19 – Protein-Membrane Interactions 20 – Protein Machines 21 – Rational Design of Protein Therapeutics 22 – Rational Drug Design